All of you know very well that DIABETES MELLITUS is a progressive state. Each and everyone with diabetes will require INSULIN at some point of the disease. Earlier, crude animal insulins were used and were very much painful. Nowadays, with recombinant technology very highly purified human Insulin is produced. Hence, less painful and less antigenic. People with diabetes now can enjoy the variety of Insulin devices and take Insulin with less pain.

2. PERMANENT INSULIN PENS: Eg. NOVOPEN-III, HUMAPEN ERGO. These pens replace cumbersome old techniques and less painful because of fine needles(31G).

3. JET INJECTORS: Insulin is pushed directly into the sub-cutanous space by pressured widely used in European countries.

4. NASAL SPRAYS AND AEROSOLS: These will be available in India by next year.

5. C.S.I.I.(Continuous Sub-cutaneous Insulin Injection): This is like an artificial pancreas. Device along with the sensor is implanted sub-cutanously and delivers insulin according to Blood sugar levels.

With more and more advances, the day may not be far away for ORAL INSULINS.